Monday 15th September 2003
Opening Session
15.00 - 17.30 Registration. The Octagon, Bath Assembly
Rooms
17.30 - 18.00 Opening of the Symposium (Richard Titball, Salisbury
UK )
18.00 - 19.00 Opening Lecture: A history of the tularemia
outbreaks and the experience of live vaccine
use in Russia (I. Mescheryakova)
19.00 - 20.00
Welcome Reception, Tea Room, Bath Assembly
Rooms.
Tuesday 16th September 2003
Genomics and post genomics
09.00 - 09.35
Sequencing of F tularensis Schu4
(Par Larsson Umea, Sweden)
09.35 - 10.10 Comparative genomics of Francisella (Emilio Garcia,
Livermore California USA)
10.10 - 10.25 A method for allelic
replacement in Francisella tularensis (I. Golovliov)
10.25 - 10.45 Coffee.
10.45 - 11.20
Francisella tularensis proteome
(Ales Macela Czech Republic)
11.20 - 11.55
Identification Of Differentially
Expressed Host Cell Transcripts In Response
To Intracellular Infection
Using Microarrays
(Anders Sjostedt, Umea Sweden)
11.55 - 13.30
Workshop and round table discussion on
F. tularensis as an
agent of bioterrorism
Epidemiology and diagnostics
13.30 - 14.05 Natural vectors of Francisella tularensis
in Scandinavia (Mats Forsman, Umea Sweden)
14.05 - 14.20 Tularemia in Kazakstan (A. Aikimayev*)
14.20 - 14.55
Diagnostic testing for F. tularensis in a public
health lab setting. (Jeannine Petersen, Colorado,
USA)
14.55 - 15.10 Tea
15.10 - 15.45 Immune response and detection of the pathogen in epidemiological
studies on tularemia (Roland Grunow, Munchen Germany)
15.45 - 16.00
Characterisation of a novicida-like
subspecies of Francisella tularensis isolated
in Australia (M. Chu)
16.00 - 16.15
DNA- based methods for taxonomy and typing of Francisella
tularensis (Anders Johansson, Umea Sweden)
16.15 - 16.50
Multiple-locus variable-number tandem repeats
and single nucleotide polymorphims reveal genetic
relationships within
Francisella tularensis (J. Farlow)
Wednesday 17th September 2003
09.00 - 09.35 The intracellular lifestyle
of Francisella tularensis (Anders Sjostedt, Umea Sweden)
09.35 - 10.10 Francisella genes required for growth and survival
in macrophages (Francis Nano, Victoria, Bristish Columbia Canada)
10.10 - 10.25 Peptides that
recognise cell surface molecules on Francisella
strains. ( V. Escuyer)
10.25 - 10.45 Coffee.
10.45 - 11.20 Poster Session
Protective Immunity to infection and vaccines
11.20 - 11.55 An overview of immunity to tularemia and vaccination
with special reference to experience in humans (Arne Tarnvik,
Umea Sweden)
11.55 - 12.10 A bioinformatic approach
to identify novel virulence determinants
common to bacterial pathogens. (A. Forsberg)
12.10 - 12.45 Characterisation and efficacy of LVS vaccination (Micheal
Green, Salisbury UK)
12.45 - 13.45 Lunch
13.45 - 14.00 CpG DNA protects against
the Live Vaccine Strain (LVS) of Francisella
tularensis but not the fully virulent strain HN63. (C. Rees)
14.00 - 14.35 Relationship between innate and adaptive immunity in
F. tularensis (Karen Elkins, Rockville, Maryland USA)
14.35 - 14.50 MglA regulates expression
of virulence factors necessary for Francisella intra-amoebae
and intra-macrophage survival and virulence. (K. Klose)
14.50 - 15.25
Immunopathogenisis of experimental infection
with virulent Francisella Tularensis in mice. (Wangxue Chen,
Ottawa, Ontario Canada)
15.25 - 15.45 Tea
15.45 - 16.20 T Cell mechanisms of controlling Francisella (Siobhan
Cowley, Victoria, British Columbia Canada)
16.20 - 16.35 Reactive nitrogen and
oxygen intermediates contribute to, but
are not essential for, killing of Francisella
tularensis by murine macrophages. (H. Lindgren)
16.35 - 17.10
Searching for subunit vaccines against
tularemia. (Wayne Conlon, Ottawa, Ontario Canada)
19.00 - 24.00 Conference Dinner. The Roman Baths & Pump
Room.
Thursday 18th September 2003
09.00 - 09.35
Characterisaiton of the
lipopolysaccharide of Francisella tularensis (Joann Prior, Salisbury UK)
09.35 - 10.10 LPS in conjugate vaccines (Malcolm Perry, Ottawa,
Ontario Canada)
10.10 - 10.25 Outer-membrane “C”-complex
from F. tularensis vaccine strain 15 protect from challenge
with F.
tularensis type A strain. (V. Zhemchugov)
10.25 - 10.45 Coffee.
Antimicrobials
10.45 - 11.00 Interleukin 12 promotes
anti-microbial clearance of pulmonary Francisella infections.
(B. Arulanandam)
11.00 - 11.35 Epidemiology of tularemia in the USA (Jacob Kool,
Fort Collins, Colorado USA)
11.35 - 12.00 Closing the symposium. (Richard Titball.
Salisbury, UK).
12.00 onwards: Lunch and departure.
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